Sister Marie Celine Janisse was born in Windsor, Ontario on February 13, 1928. She was one of the seven children of Norman Janisse and Eva Tino, both of Windsor. She had her reception at Sacred Heart Convent in London, Ontario on August 25, 1946. Her first profession was August 25, 1948, and her final profession was August 25, 1951.

Sister Marie Celine received a Fine Art diploma from the Institute of Pedagogy, Montreal in 1952-53. She was awarded her Bachelor of Fine Arts degree from the University of Notre Dame in Indiana in 1969.

Sister Marie Celine served as a parish worker in Peru from August 2, 1983 to December 1, 1994. Upon her return to Canada, she was involved in Heart-Links, an organization started by the Sisters of St. Joseph to support community development in Peru. She returned to Peru from 1998 to 2000 to work for Heart-Links. After this, she served on pastoral and art projects with the Sisters of St. Joseph of Pembroke mission to Chincha, Peru from 2001 to 2003, and then again with Heart-Links in London from 2003 to 2007. Sister Marie Celine also served in Nicaragua as part of the Hurricane Mitch Response, for three months from 1998-1999.